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Cognitive Remediation and Neuroimaging Laboratory


The Cognitive Remediation and Neuroimaging Lab conducts innovative research with aims to better understand and treat cognitive difficulties in mental health disorders, such as depression and schizophrenia. We use brain imaging techniques to better understand brain correlates of neurocognitive and social cognitive impairments in various mental health disorders, as well as in youth at risk of developing these disorders. We are also interested in using digital technologies, such as smartphones and virtual reality, to develop better cognitive assessment tools and treatments to ultimately improve quality of life in individuals with mental health disorders.

Research Interests

  • Cognitive impairments in mental health disorders

  • Brain imaging

  • Neurocognition

  • Social cognition

  • Cognitive remediation

  • Cognitive assessment

  • Digital technologies

  • Virtual reality


Synthia Guimond

Ph. D.


Significant Work

  • Guimond, S., Ling, G., Drodge, J., Matheson, H., Wojtalik, J. A., Lopez, B., Collin G, Brady R, Mesholam-Gately RI, Thermenos H, Eack SM, Keshavan, M. S. (in press). Functional Connectivity Associated with Improvement in Emotion Management after Cognitive Enhancement Therapy in Early-Course Schizophrenia. Psychological Medicine.

  • Noël, C., Gu, F., Ormston, L., Tingue, S., Tucci, A., Pezzoli, P., Padani, S., Sandoval, L., Wojtalik, J., Eack, S., Keshavan, M., Guimond, S. (in press). Cognitive Enhancement Therapy in Early Schizophrenia: A Qualitative and Quantitative Case Series of Patients’ Experiences. Journal of Psychosocial Rehabilitation and Mental Health.

  • Guimond, S., Sandoval, L. R., & Keshavan, M. (2020) Schizophrenia, Book chapter in Chiaravalloti N., & Weber E., Cognitive Rehabilitation: Examining the Evidence from Brain to Behavior, Springer Publishing Company.

  • Guimond, S., Keshavan, M.S., Torous, J.B. (2019). Towards remote digital phenotyping of cognition in schizophrenia, Schizophrenia Research, 208, 36-38.

  • Kelly, S.*, Guimond, S.*, Lyall, A., Stone, W. S., Shenton, M. E., Keshavan, M.S., & Seidman, L. J. (2019). Neural correlates of cognitive deficits across developmental phases of schizophrenia. Neurobiology of Disease.

  • Guimond, S., Padani, S., Lutz, O., Eack, S., Thermenos, H., & Keshavan, M. (2018). Impaired regulation of emotional distractors during working memory load in schizophrenia. Journal of psychiatric research, 101, 14.

  • Guimond, S., Béland, S., & Lepage, M. (2018). Strategy for Semantic Association Memory (SESAME) training: Effects on brain functioning in schizophrenia. Psychiatry Research: Neuroimaging, 271, 50-58.

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